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About this product

Division: Spine
Category: Cervical

ZERO-P VA Spacer is a stand-alone anterior cervical interbody fusion device designed to combine the functionality and benefits of a cervical interbody spacer and an anterior cervical plate.1-4

The ZERO-P VA Spacer is designed to both minimize contact with local anatomical structures and to prevent contact with adjacent level discs. ZERO-P VA Spacer features two variable angle screws for fixation into adjacent vertebral bodies. 

ZERO-P VA Spacer is designed for surgeons focused on ease of use and/or surgeons preferring non-rigid screw constructs.

Disclaimers/ Footnotes:
1. Kaiser, M.G., R.W. Haid Jr., B.R. Suback, et al. 2002. “Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft”. Neurosurgery 50: 229-236.
2. Caspar, W.,F.H Geisler, T. Pitzen, et a;. 1998. “Anterior Cervical plate stabilization in one and two level degenerative disease: overtreatment or benefit?” J. Spinal Disord. 11: 1-11.
3. Mobbs, R.J., P. Rao and N.K. Chandran. 2007. “Anterior cervical discectomy and fusion: analysis of surgical outcome with and without plating”. J. Clin. Neurosci. 14:639-642.
4. Moftakhar,R and G.R. Trost. 2004. “Anterior cervical plates: a historical perspective”. Neurosurg. Focus. 16:E8.

ZERO-P VA Stand-alone Spacer | DePuy Synthes Companies

Indications for Use



The DePuy Synthes ZERO-P VA is a stand-alone anterior cervical interbody fusion device indicated for use in skeletally mature patients with degenerative disc disease (DDD) with accompanying radicular symptoms at one level from C2-T1. DDD is defined as discogenic pain with degeneration of the disc confirmed by history and radiographic studies. These patients should have had six weeks of non-operative treatment. The interior of the spacer component of the Synthes ZERO-P VA should be packed with autogenous bone graft and implanted via an anterior approach. 





  1. Use of the DePuy Synthes ZERO-P VA is contraindicated when there is active systemic infection, infection localized to the site of the proposed implantation, or when the patient has demonstrated allergy or foreign body sensitivity to any of the implant materials.
  2. Severe osteoporosis may prevent adequate fixation and thus preclude the use of this or any other orthopaedic implant.
  3. Conditions that may place excessive stresses on bone and implants, such as severe obesity or degenerative diseases, are relative contraindications. The decision whether to use these devices in patients with such conditions must be made by the physician taking into account the risks versus the benefits to the patient.
  4. Use of these implants is relatively contraindicated in patients whose activity, mental capacity, mental illness, alcoholism, drug abuse, occupation, or lifestyle may interfere with their ability to follow postoperative restrictions, thereby placing undue stresses on the implant during bony healing. This could result in a higher risk of implant failure.
  5. Prior fusion at the level to be treated.
  6. Any condition not described in the Indications for Use.




One of the risks of any surgical procedure is death. Other potential risks which may require additional surgery, include:


  • device component fracture
  • loss of fixation
  • pseudoarthrosis (i.e., non-union)
  • fracture of the vertebrae*
  • neurological injury*
  • vascular or visceral injury*


*These risks can also be associated with general risks of surgery.


Discard and DO NOT USE previously opened or damaged devices.  Use only devices that are packaged in unopened and undamaged packages. DO NOT USE if there is a loss of sterility of the device. DO NOT USE past the expiration date. 


The DePuy Synthes ZERO-P VA cervical intervertebral body fusion devices are sterilized by gamma radiation. DO NOT RESTERILIZE. CONTENTS STERILE UNLESS INNER PACKAGE IS OPENED OR DAMAGED.


Components of ZERO-P VA should not be used in conjunction with components of, competing systems not manufactured by Synthes. In addition, mixing titanium or titanium alloy with stainless steel implant components is not recommended for metallurgical, mechanical and functional reasons.  


Features & Benefits

  Features Benefits

ZERO-P VA Stand-alone Spacer variable angle insertion | DePuy Synthes Companies

ZERO-P VA Stand-alone Spacer screw | DePuy Synthes Companies

ZERO-P VA Stand-alone Spacer variable angle screws | DePuy Synthes Companies

ZERO-P VA Stand-alone Spacer rendering | DePuy Synthes Companies

Zero profile midline

Designed to minimize contact with local anatomical structures.


Designed to prevent contact with adjacent level discs.


May be used to facilitate surgeries where Zero-P VA is implanted adjacent to previous fusions

Two variable angle screws Screws may be inserted at shallower angles; larger allowable range for screw insertion (17° range cranial-caudal, 14° range medial-lateral)
Contra-lateral safety stops added to interbody plate Designed to minimize risk of over insertion in the posterior direction during initial insertion and during final tightening
One step passive screw securing. Audible, visual, tactile cues to indicate secured screw.
2 footprints, 8 heights, 3 sagittal profiles Multiple implant options designed to accommodate various patient anatomy 


DSUS/SPN/0616/1356 08/2016

All medical devices have associated risks. Please refer to the package insert and other labeling for a complete list of indications, contraindications, precautions and warnings. For further information on DePuy Synthes Products, please contact your local DePuy Synthes Representative.
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