MILAGRO® ADVANCE Interference Screw

Division: Sports Medicine
Category: ACL Reconstruction

The Interference Screw, Redefined.

The MILAGRO® ADVANCE Interference Screw utilizes an advanced screw design that offers exceptional bone engagement and rapid insertion. It comes available in Mitek Sports Medicine proprietary BIOCRYL RAPIDE® Biocomposite Material as well as PEEK Material.

Indications for Use

Attachment of soft tissue grafts or bone-tendon-bone grafts to the tibia and or femur during cruciate ligament reconstruction procedures. Additionally 7, 8, 9, x23mm screws are indicated for medial & lateral collateral ligament repair, medial patellofemoral ligament reconstruction (femur fixation) of the knee, proximal bicep tenodesis in shoulder and distal biceps in the elbow.

Features & Benefits

MILAGRO ADVANCE Interference Screw dramatically improves ease of use compared to traditional interference screws:


Features Benefits
Bony ingrowth BIOCRYL RAPIDE Biocomposite Material promotes bony ingrowth at the implant site1-2
Rapid insertion Inserts approximately 2x faster than traditional interference screws3
Strong fixation Improved interdigitation of graft threads increases overall fixation strength by 25%3
Effortless bone engagement Unique Distal-tip requires 83% less effort to achieve bone engagement3
Robust yet gentle insertion Ease of bone engagement and lower insertion torque ensure robust insertion into hard bone with minimal torque transmission to soft tissue grafts and tendons
Material choice Available in BIOCRYL RAPIDE Biocomposite Material and PEEK



  1. Barber FA, Dockery WD, Hrnack SA, Long-term degradation of a poly-lactide co-glycolide/β-tricalcium phosphate biocomposite interference screw. Arthroscopy. 2011;27(5):637-643
  2. Gladstone J, Gaskin CM. 3 year resorption and replacement pattern of a biocomposite interference screw (PLLA/PGA/BTCP) used in tibial soft tissue graft fixation for ACL reconstruction. 2012 AANA Arthroscopy Association of North America Annual Meeting.
  3. DOCUMENT NO.: 300418 REV. B DCN 19733
DSUS/MTK/0717/1043 11/2017

All medical devices have associated risks. Please refer to the package insert and other labeling for a complete list of indications, contraindications, precautions and warnings. For further information on DePuy Synthes Products, please contact your local DePuy Synthes Representative.