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About this procedure

MONOVISC® High Molecular Weight Hyaluronan is an FDA-approved treatment made from ultra-pure hyaluronan, a naturally occurring lubricant found in healthy knee joints.

MONOVISC is single injection with efficacy lasting up to 6 months in pain relief due to knee osteoarthritis. MONOVISC is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics, e.g. acetaminophen. MONOVISC may enhance the viscoelastic properties of synovial fluid to relieve pain and increase mobility.

Important Safety Information:
MONOVISC High Molecular Weight Hyaluronan is indicated in the treatment of pain in osteoarthritis (OA) of the
knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy
and to simple analgesics, e.g., acetaminophen. In clinical studies, the most commonly
reported adverse events were arthralgia, joint swelling and injection site pain.
MONOVISC is contraindicated in patients with known hypersensitivity to
hyaluronate formulations or known hypersensitivity (allergy) to gram positive
bacterial proteins. MONOVISC should not be injected in patients with infections or
skin diseases in the area of the injection site or joint. MONOVISC should not be administered to patients with known bleeding disorders.
MONOVISC High Molecular Weight Hyaluronan

Products for this Procedure

Patient Materials

Patient education brochure

DSUS/MTK/0614/0141
Please refer to the package insert for a complete list of indications, contraindications, precautions and warnings.
For further information on DePuy Synthes products, please contact your local DePuy Synthes representative.
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