AOX™ Antioxidant Polyethylene

Division: Knee
Category: Primary Knees

DePuy Synthes Joint Reconstruction, a leader in researching and producing polyethylene, is proud to offer the next generation of polyethylene, AOX™ Polyethylene. This advanced material, introduces a unique antioxidant, COVERNOX™ Antioxidant, which combines with post irradiation free radicals to stabilize them. Once implanted, the COVERNOX™ Antioxidant which has bonded with free radicals, prevents oxidation to maintain mechanical integrity and oxidative stability.

Indications for Use

Total knee arthroplasty is intended to provide increased patient mobility and reduced pain by replacing the damaged knee joint articulation in patients where there is evidence of sufficient sound bone to seat and support the components. Total knee replacement may be considered for younger patients if, in the opinion of the surgeon, an unequivocal indication for total knee replacement outweighs the risks associated with the age of the patient, and if limited demands regarding activity and knee joint loading can be assured.

Features & Benefits

Features Benefits
Oxidative Stability • The polyethylene resin is blended with an antioxidant (COVERNOX Antioxidant). The antioxidant stabilizes free radicals preventing them from oxidizing.
Wear Resistance • The polyethylene resin/COVERNOX Antioxidant mix is exposed to a level of irradiation (8 Mrads) to stimulate a moderate amount of cross-linking while delivering optimum wear characteristics without compromising mechanical integrity.
Mechanical Integrity • AOX Polyethylene maintains high material strength and toughness characteristics by utilizing GUR 1020 resin, with its better inherent mechanical properties, than GUR 1050.1

• The addition of an antioxidant into the material eliminates the need for re-melting or annealing, and therefore it maintains excellent mechanical properties.2

1 ASTM Standard Specification for Ultra-High-Molecular-Weight Polyethylene Powder and Fabricated Form for Surgical Implants, F 648-00.
2 Kurtz, S. M., UHMWPE Biomaterials Handbook, 2nd ed., page 73-74.

All medical devices have associated risks. Please refer to the package insert and other labeling for a complete list of indications, contraindications, precautions and warnings. For further information on DePuy Synthes Products, please contact your local DePuy Synthes Representative.